Phospholipid-bound choline to support cellular function, cognitive function and liver health‡
- Phospholipid-bound choline to support cellular function, cognitive function and liver health‡
- Acts as a precursor for phospholipids and acetylcholine, a neurotransmitter involved in attention, memory and neuromuscular function‡
- Supports fat metabolism in the liver to promote energy production‡
- Provides choline source for pregnancy to support infant cognitive development‡
- Soy-free, sunflower-derived phosphatidylcholine.
- Part of the PureGenomics® product line
- Made with high-quality ingredients backed by verifiable science
Indications
- Ages 18 and up
- Healthy liver function‡
- Cellular health support‡
- Pregnancy support‡
Suggested Use
As a dietary supplement, take 2 capsules daily, with a meal.
Science & Research
Verifiable Science
Phosphatidylcholine (PC) is a naturally occurring, integral component of the cellular membrane, adding fluidity and strength to cells. It serves as a source of choline, an important nutrient for methylation, cell-to-cell communication, cognition and liver function.1 Choline and its metabolites are the major source of methyl groups in the diet. Methylation plays many roles including neurotransmission, vitamin assimilation, DNA synthesis and gene regulation.2 Choline is required for the synthesis of phospholipids and acetylcholine, a neurotransmitter involved in attention, learning and memory. A 6-month double-blind, placebo-controlled trial suggested that choline-containing lecithin, alpha GPC supports memory in aging individuals. Animal research suggests an adaptogenic effect when exposed to stress.3 Certain genetic variations in MTHFR and PEMT, enzymes that play critical roles in methylation and choline synthesis, respectively, have been associated with increased dietary choline needs.4
Research indicates that choline intake is important for pregnant women, particularly those with PEMT and MTHFR genetic variations.5 Another clinical trial showed that women with PEMT and MTHFR genetic variations who consumed 480 mg of choline daily during pregnancy had offspring with faster processing speed than those who did not.6 PC also plays a significant role in the healthy transport and metabolism of lipids. A randomized, double blind, placebo-controlled trial suggested that choline-containing lecithin may help support healthy hepatic fat metabolism.7 Animal studies indicate that PC promotes healthy liver and pancreatic antioxidant activity.‡
References
da Costa KA, et. al. Am J Clin Nutr.2006 Jul;84(1):88-94.
Olthof MR, et.al. Am J Clin Nutr. 2005 Jul;82(1):111-7.
Kumar R, et. al. J Altern Complement Med. 2002 Aug;8(4):487-92
West AA, et. al. J Acad Nutr Diet.2014 Oct;114(10):1594-600
Yan J, et. al. Am J Clin Nutr.2012 May;95(5)
Caudill MA, et al. FASEB J.2018 Apr;32(4):2172-2180
Fischer LM, et. al. Am J Clin Nutr.2010 Nov; 92(5): 1113?119.
‡These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.